Bacterial Vaginosis (BV) Is A Synergistic Polymicrobial Syndrome

.....The normal vaginal flora is characterized by high concentrations of Lactobacillus species (108 colonyforming units/mL) and a pH of 4.7 or less.......

Lactobacilli that produce hydrogen peroxide, primarily Lactobacillus crispatus and Lactobacillus jensenii, are critical in maintaining this pH and in controlling growth of other commensal flora.

Bacterial vaginosis (BV) is a synergistic polymicrobial syndrome characterized by depletion of Lactobacillus species, especially those that produce........

........Efforts to optimize treatment and prevention of BV have been limited by a lack of knowledge about the etiology of the initial decline of hydrogen peroxide-producing lactobacilli that precedes the increase in vaginal anaerobes.

Because the inciting event is unknown, treatment of BV aims to reduce the vaginal burden of these anaerobes and...........

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